Vysis® LSI® 4q12 Tricolor, Rearrangement Probe
Product Description
| Probe Name | Probe Location | Fluorophore |
| Vysis LSI SCFD2 | 4q12 | SpectrumGreen TM |
| Vysis LSI LNX | 4q12 | SpectrumOrange TM |
| Vysis LSI PDGFRA/KIT | 4q12 | SpectrumAqua TM |
The Vysis LSI 4q12 Tri-Color Rearrangement Probe consists of three differently colored probes all located in the FIP1L1-PDGFRA region of chromosome 4q12. The SpectrumGreen probe begins approximately 75 kb centromeric to the FIP1L1 gene and extends toward the centromere for approximately 700 kb. The SpectrumOrange probe starts about 25 kb telomeric of the FIP1L1 gene, extends toward the 4q telomere for about 450 kb, and contains the LNX gene. The SpectrumAqua probe begins between exons 15 and 16 of the PDGFRA gene, extends toward the 4q telomere for approximately 770 kb, and contains the KIT gene.
Probe Map
Figure 1. Normal nucleus showing the two tricolor green/orange/aqua fusion signals.
Figure 2. Abnormal nucleus showing the one tricolor green/orange/aqua fusion signal and one green/aqua fusion signal.
Analyte Specific Reagent.
Analytical and performance characteristics are not established.
Analytical and performance characteristics are not established.
