Vysis® LSI® IGH/MALT1 t(14;18) (q32;q21) Dual Color, Dual Fusion Translocation Probe
Product Description
| Probe Name | Probe Location | Fluorophore |
| Vysis LSI IGH | 14q32 | SpectrumGreen TM |
| Vysis LSI MALT1 | 18q21 | SpectrumOrange TM |
The LSI IGH is a 1.5 Mb probe that hybridizes to the 14q32 region on chromosome 14 and contains sequences homologous to essentially the entire IGH locus, as well as sequences extending ~ 300 kb beyond the 3' end of the IGH locus. LSI IGH is labeled in SpectrumGreen. The 670 kb SpectrumOrange labeled LSI MALT1 probe hybridizes to chromosome 18q21. It contains the entire 79 kb MALT gene and flanking sequences on either side of the gene. The probe extends from a point centromeric of the HAK gene to telomeric of the marker D18S531.
Probe Map
Results of Hybridization
In a normal cell, a two orange, two green signal pattern will be observed.
Result of the hybridization of the LSI IGH/MALT1 t(14;18)(q32;q21) Dual Color, Dual Fusion Translocation Probe as observed in normal interphase cells.
An abnormal cell hybridized with the LSI IGH/MALT1 t(14;18)(q32;q21) Dual Color, Dual Fusion Translocation Probe. The cell in this image shows the one orange, one green and two fusion signal pattern.
Analyte Specific Reagent.
Analytical and performance characteristics are not established.
Analytical and performance characteristics are not established.
