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Vysis MultiVysion PB Multi-color Probe Kit

CE Marked

Product Probe Description

Probe Name Probe Location Fluorophore
Vysis LSI 13 13q14 SpectrumRed
Vysis LSI 21 21q22.13-22.2 SpectrumGreen
Vysis LSI 22 22q11.2 SpectrumGold
Vysis CEP 16 16q11.2 Satellite II DNA SpectrumAqua
Vysis CEP 18 18p11.1-q11.1 Alpha Satellite DNA SpectrumBlue

Product Description

MultiVysion PGT and MultiVysion PB fluorescence in situ hybridization (FISH) probe sets are designed for determination of chromosome copy number in single cells.

Unlabeled DNA is included with both probe sets to block sequences contained within the target loci that are common to other chromosomes. This probe set is premixed in Hybridization Buffer.


Probe Mixtures

Probe Mixture #1
LSI 13:
DNA probe spanning the RB1 (13q14) labeled with SpectrumRed.
CEP 16:
D16Z3 satellite II DNA probe corresponding to 16q11.2 labeled with SpectrumAqua.
CEP 18:
D18Z1 alpha-satellite DNA probe corresponding to 18p11.1-q11.1 labeled with SpectrumBlue.
LSI 21:
DNA probe corresponding to loci D21S341, D21S342, D21S339, EGR, and D21S338 (21q22.13-q22.2) labeled
with SpectrumGreen.
LSI 22:
DNA probe corresponding to the BCR locus (22q11.2) labeled with SpectrumGold.


Results of Hybridization

Hybridization_Normal
MultiVysion PB hybridized to an embryonic cell.

Probe Maps

Probe_Map_LSI_13_RB-1_13q14Probe_Map_LSI_21_21q22.13-q22.2Probe_Map_LSI_22q11.2
Ideograms

Ideogram_13q14_LSI_13RedIdeogram_16q11.2_CEP_16_satellite_IIIdeogram_18p11.1q11.1_CEP_18_alpha_satelliteIdeogram_21q22.13-q22.2_LSI_21GreenIdeogram_22q11.2_LSI_22Gold

CE Marked