Breast Cancer

The detection of genetic aberrations in solid tumors with DNA Fluorescence in situ Hybridization (FISH) probe technology is a powerful means to diagnose and more efficiently treat a wide range of cancers. Vysis offers a comprehensive line of direct labeled DNA probes for solid tumor assessment. Single and multi-color probe sets offer researchers and clinicians a variety of ways to identify chromosome or locus deletions, gains, or translocations that have been associated with specific types of solid tumors. These probes can be applied to a variety of sample types prepared for metaphase or interphase analysis.

The probes for oncology, cytology, and pathology provide the following advantages:

• Specific high-intensity signals without amplification and detection steps
• Low background for easy analysis
• Rapid, convenient, and easy-to-use assays
• Many probes designed for gene amplification detection include internal control probes
• Protocols that offer hybridization as quickly as four hours on the HYBriteTM Denaturation and Hybridization System
• Solid tumor probes have been optimized for paraffin-embedded tissues